Granulosa cell tumor in a six-year-old girl presented as precocious puberty

نویسندگان

  • Mahin Hashemipour
  • Mohammad Hassan Moaddab
  • Masoud Nazem
  • Parvin Mahzouni
  • Mehdi Salek
چکیده

Ovarian sex cord-stromal tumors, including granulose cell tumors (GCTs), are a group of neoplasms that occur rarely, especially in children. Only 0.1 percent of all ovarian tumors and 4-5 percent of GCTs occur in children. The most common presentation of these tumors in children is precocious puberty. We report a 6 years old girl with isosexual precocity, presented as premature thelarche and vaginal bleeding. Ultrasonography of pelvis showed a hypoechoic solid mass of left ovary.Microscopic features of the resected mass were characteristic of juvenile GCT. Although in most of girls with precocious puberty, the etiology is idiopathic, important causes, such as ovarian tumors must be considered.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Investigation of the Cause of Precocious Puberty in an 8-Year-Old Girl Ended up in Juvenile Granulosa and Theca Cell Tumor of the Ovary

Isosexual precocious puberty in girls has several etiologies. Juvenile granulose cell tumor is one of the rarest causes that only stands for 1.5% of ovarian cancers. This tumor mostly encounters in first 2 decades of life. This paper is a report of an 8-year-old girl with precocious puberty that within five months developed breast enlargement followed by menarche. Works which are done to find t...

متن کامل

گزارشی از بلوغ زودرس کاذب در یک دختر 4 ساله

Precocious puberty may be classified as true precocious puberty or precocious pseudopuberty. The latter one in females may be in sexual (feminization) or hereto sexual (virilization). Ovarian tumors may be iso sexual call tumor, teratoma, etc, are among the etiologic factors of precocious psudopuberty. This paper presents a 4-year girl was admitted to the hospital with severe abdominal pain. ...

متن کامل

Central Precocious Puberty and Granulosa Cell Ovarian Tumor in An 8-Year Old Female

Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are of common presentation. We describe here a rare case of juvenile granulosa cell tumor in a female with central precocious puberty (CPP). An 8-year old girl with CPP presented with vaginal bleeding four months after the diagnosis and before starting treatment with gonadotropin-releasing hormone (G...

متن کامل

Progesterone Producing Granulosa Cell Tumor: a Case Report

The granulosa cell tumor is the most common malignant functioning tumor of the ovary. When functional, granulosa tumor almost always are estrogenic although rare tumors are androgenic. Progesterone producing by these tumors has only been reported twice. We report a case of granulosa cell tumor in a 7 years old girl with precocious puberty who represent the first case of progesterone producing b...

متن کامل

Premature Thelarche and Precocious Puberty in a Three-Year-Old Girl with Granulosa Cell Tumor

Granulosa cell tumors (GCTs) are tumors that arise from granulosa cells, occurring in women 50 to 55 years of age but may occur at any age whereas Juvenile granulosa cell tumors usually occur in children and adolescents. A three years old girl with breast development but without any significant past medical history was referred to the Pediatric Clinic in Children hospital(University of Medical ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2010